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Search results for: written by "Jim McWhir"/ (Protocol search)
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Pub. Date:
Jan-09-2002;
DOI:10.1385/1-59259-178-7:003
Summary: In 1980, Gordon et al. (1) showed that DNA injected into the pronuclei of single-cell embryos could be incorporated, expressed, and transmitted to the offspring of transgenic mice. Since then, pronuclear...
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Pub. Date:
Mar-24-2004;
DOI:10.1385/1-59259-741-6:301
Summary: Every cell in a mammal, other than odd exceptions (e.g. mature erythrocytes or lymphocytes with rearranged antigen receptors) contains a complete complement of the genetic information required to build...
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Pub. Date:
Mar-24-2004;
DOI:10.1385/1-59259-741-6:099
Summary: Embryonic stem (ES) cells have the developmental capability to contribute to every cell type of the adult mouse when reintroduced into the blastocyst embryo (1,2). They can be easily manipulated in...
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Pub. Date:
Mar-01-2006;
DOI:10.1385/1-59745-046-4:77
Summary: Human embryonic stem cells provide both an in vitro model of human development and a potential source of cells for treatment of degenerative, metabolic, or traumatic disorders. This chapter describes...
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Pub. Date:
Dec-05-2005;
DOI:10.1385/1-59745-005-7:81
Summary: Cells of different types can be induced to fuse by electroshock. Cells of one type are typically dominant and are able to reprogram the nuclei derived from cells of the other type, in fusion hybrids...
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