SpringerProtocols: Abstract: 6. Measurement of Radioligand Binding by Scintillation Proximity Assay

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6. Measurement of Radioligand Binding by Scintillation Proximity Assay

By: Jenny Berry², Molly Price-Jones²

Abstract

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Scintillation proximity assay (SPA) is a homogeneous assay technology (1) which is bead-based and removes the need for a filtration step to separate bound from free ligand in a receptor-binding assay. The principle of the technology is shown in Fig. 1 .

Affiliation(s): (2) The Maynard Centre, GE Healthcare Biosciences, Cardiff, UK

Book Title: Receptor Binding Techniques

Series: Methods in Molecular Biology | Volume: 306 | Pub. Date: Mar-25-2005 | Page Range: 121-138 | DOI: 10.1385/1-59259-927-3:121

Subject: Neuroscience

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