Springer Protocols: Abstract: 12. Application of Proteomics and Protein Analysis for Biomarker and Target Finding for Immunotherapy

12. Application of Proteomics and Protein Analysis for Biomarker and Target Finding for Immunotherapy

By: Petra Weingarten³, Petra Lutter³, Andreas Wattenberg³, Martin Blueggel³, Sonja Bailey³, Joachim Klose⁴, Helmut E.⁵, Christoph Huels⁵

Abstract

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Regulatory T-cells play a central role in the maintenance of the immunological balance and are powerful inhibitors of T-cell activation both in vivo and in vitro. The enhancement of suppressor-cell function might be a target for immunotherapeutic approaches for the treatment of immune-mediated diseases like multiple sclerosis and Crohn’s disease.

Affiliation(s): (3) Protagen AG, Dortmund, Germany
(4) Institute for Human Genetics, Charité, Berlin, Germany
(5) Medical Proteom-Center, Ruhr-University Bochum, Bochum, Germany

Book Title: Adoptive Immunotherapy: Methods and Protocols

Series: Methods in Molecular Medicine | Volume: 109 | Pub. Date: Nov-30-2004 | Page Range: 155-173 | DOI: 10.1385/1-59259-862-5:155

Subject: Immunology

References

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