SpringerProtocols: Abstract: Immunohistochemistry and In Situ Hybridization in Pancreatic Neoplasia

Immunohistochemistry and In Situ Hybridization in Pancreatic Neoplasia

By: Robb E. Wilentz², Ayman Rahman², Pedram Argani², Christine Iacobuzio-Donahue²

Abstract

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There are many types of pancreatic neoplasms. Pathologic examination, which includes both routine (e.g., hematoxylin-and-eosin staining) and ancillary (e.g., immunohistochemistry and in situ hybridization) techniques, is essential in correctly typing a pancreatic neoplasm. This chapter focuses on the use of immunohistochemistry and in situ hybridization in the differentiation of pancreatic neoplasms. The materials and methods of these two techniques are described in detail.

Affiliation(s): (2) Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD

Book Title: Pancreatic Cancer: Methods and Protocols

Series: Methods in Molecular Medicine | Volume: 103 | Pub. Date: Nov-12-2004 | Page Range: 67-88 | DOI: 10.1385/1-59259-780-7:067

Subject: Cancer Research

Key Words: Pancreatic cancer - pancreas - ductal adenocarcinoma - immunohistochemistry - in situ hybridization

References

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