SpringerProtocols: Abstract: In Situ End-Labeling of Fragmented DNA and the Localization of Apoptosis

In Situ End-Labeling of Fragmented DNA and the Localization of Apoptosis

By: Tim D. Hewitson², Teresa Bisucci³, Ian A. Darby³

Abstract

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Apoptosis is a morphologically distinct form of programmed cell death. It has a role in such processes as embryogenesis, immune regulation, and defense against viruses, and can also be induced by a variety of physical and chemical stimuli (1). Importantly apoptosis leads to the safe removal of cells by phagocytosis, whereas in contrast, necrosis provokes tissue injury and inflammation.

Affiliation(s): (2) Department of Nephrology, Royal Melbourne Hospital, Victoria, Australia
(3) Wound Healing and Microvascular Biology Group, Department of Human Biology and Movement Science, RMIT University, Bundoora, Victoria, Australia

Book Title: In Situ Hybridization Protocols

Series: Methods in Molecular Biology | Volume: 123 | Pub. Date: Sep-01-1999 | Page Range: 157-164 | DOI: 10.1385/1-59259-677-0:157

Subject: Cell Biology

References

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