SpringerProtocols: Abstract: Growth Cones of Living Neurons Probed by Atomic Force Microscopy

Growth Cones of Living Neurons Probed by Atomic Force Microscopy

By: Davide Ricci³, Massimo Grattarola³, Mariateresa Tedesco³

Abstract

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A large body of recent literature describes the use of atomic force microscopy (AFM; ref. 1) for the study of living cells. These experimental findings clearly indicate that AFM is a very valuable tool for the 3D imaging of flat biological samples strongly adhering to a substrate, with a lateral resolution in between the resolutions of optical and electron microscopy. Moreover, a very relevant feature of AFM is its capability of analyzing local mechanical properties of living cells.

Affiliation(s): (3) Department of Biophysical and Electronic Engineering, University of Genoa, Genoa, Italy

Book Title: Atomic Force Microscopy: Biomedical Methods and Applications

Series: Methods in Molecular Biology | Volume: 242 | Pub. Date: Oct-02-2003 | Page Range: 125-140 | DOI: 10.1385/1-59259-647-9:125

Subject: Imaging/Radiology

References

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