SpringerProtocols: Abstract: 6. Identification of Start Sites of Bi-Directional DNA Synthesis at Eukaryotic DNA Replication Origins

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6. Identification of Start Sites of Bi-Directional DNA Synthesis at Eukaryotic DNA Replication Origins

By: Alessandro Vindigni², Gulnara Abdurashidova², Arturo Falaschi²

Abstract

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DNA replication is the key process for the conservation and transmission of genetic information in all living organisms. The bi-directional DNA replication does not start randomly along the genome but rather at precise chromosomal regions, defined as origins of DNA replication where, after specific protein-DNA interactions, regulation of the process occurs.

Affiliation(s): (2) International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

Book Title: Mammalian Artificial Chromosomes: Methods and Protocols

Series: Methods in Molecular Biology | Volume: 240 | Pub. Date: Nov-30-2003 | Page Range: 105-122 | DOI: 10.1385/1-59259-434-4:105

Subject: Genetics/Genomics

References

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