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Classification of Protein Folds
Abstract
The classification of three-dimensional (3D) structures now plays a central role in understanding the principles of protein structure, function, and evolution. Classification of new structures can provide functional details through comparison to others, which is of growing importance as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy can now produce structures in advance of biochemical characterization (e.g., ref. 1). More generally, structure classifications themselves provide an excellent source of data for analyzes of all kinds.
Affiliation(s): (2) Research and Development, Bioinfomatics Research Group, SmithKline Beecham Pharmaceuticals, Essex, UK
Series: Methods in Molecular Biology  |  Volume: 143  |  Pub. Date: Aug-15-2000  |  Page Range: 305-324  |  DOI: 10.1385/1-59259-368-2:305
Subject:  Protein Science
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