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Humanization of Monoclonal Antibodies by CDR Grafting
Abstract
The discovery of the process for making rodent monoclonal antibodies (MAbs) 26 years ago by Kohler and Milstein has led to a revolution in the treatment of over 50 major diseases, and has borne an industry whose products today represent 6% of total biotechnology sales. The full potential of this industry has still to be reached.
Affiliation(s): (3) AERES Biomedical Ltd., London, UK
Series: Methods in Molecular Biology  |  Volume: 207  |  Pub. Date: Sep-16-2002  |  Page Range: 81-100  |  DOI: 10.1385/1-59259-334-8:81
Subject:  Cancer Research
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