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Leukocyte Transmigration Through Vascular Endothelium: An In Vitro Method
Abstract
The endothelial lining of blood vessels forms an intact monolayer throughout the vascular system, and constitutes a critical barrier between the blood flow and the tissues beneath. Endothelial cells (EC) have a prominent role in the regulation of hemostasis, immunity, and inflammation; in particular, EC are active participants in regulating the traffic of cells and substances from blood to tissues and vice-versa (1,2).
Affiliation(s): (2) Laboratory for Cellular Immunology, Department of Immunology and Cell Biology, Mario Negri Institute for Pharmacological Research, Milano, Italy
Series: Methods in Molecular Biology  |  Volume: 96  |  Pub. Date: Feb-01-1999  |  Page Range: 171-176  |  DOI: 10.1385/1-59259-258-9:171
Subject:  Cell Biology
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