| 1. |
Björntorp, P., Karlsson, M., Pertoft, H., Pettersson, P., Sjöström, L., and Smith, U. (1978) Isolation and characterization
of cells from rat adipose tissue developing into adipocytes. J. Lipid Res.
19, 316–324.
|
| |
| 2. |
Hausman, G. J., Campion, D. R., and Martin, R. J. (1980) Search for the adipocyte precursor cell and factors that promote
its differentiation. J. Lipid Res.
21, 657–670.
|
| |
| 3. |
Cryer, A. (1985) Biochemical markers of adipocyte precursor differentiation, in New Perspectives in Adipose Tissue: Structure, Function and Development, (Cryer, A. and Van, R. L. R., eds.), Butterworth, London, pp. 383–405.
|
| |
| 4. |
Cameron, I. L. and Smith, R. E. (1964) Cytological responses of brown fat tissue in cold-exposed rats. J. Cell Biol.
23, 89–100.
|
| |
| 5. |
Hunt, T. E. and Hunt, E. A. (1967) A radioautographic study of proliferation in brown fat of the rat after exposure to cold.
Anat. Rec.
157, 537–546.
|
| |
| 6. |
Bukowiecki, L. J., Géloen, A., and Collet, A. J. (1986) Proliferation and differentiation of brown adipocytes from interstitial
cells during cold acclimation. Am. J. Physiol.
250, C880–C887.
|
| |
| 7. |
Rehnmark, S. and Nedergaard, J. (1989) DNA synthesis in mouse brown adipose tissue is under β-adrenergic control. Exp. Cell Res.
180, 574–579.
|
| |
| 8. |
Néchad, M. and Olson, L. (1983) Development of interscapular brown adipose tissue in the hamster. II. Differentiation of transplants
in the anterior chamber of the eye: Role of the sympathetic innervation. Biol. Cellulaire
48, 167–174.
|
| |
| 9. |
Cannon, B., Matthias, A., Golozoubova, V., Ohlson, K. B. E., Andersson, U., Jacobsson, A., and Nedergaard, J. (1999) Unifying
and distinguishing features of brown and white adipose tissues: UCP1 versus other UCPs, in Progress in Obesity Research 8, (Ailhaud, G. and Guy-Grand, B., eds.), John Libbey, London, pp. 13–26.
|
| |
| 10. |
Klaus, S., Choy, L., Champigny, O., Cassard-Doulcier, A.-M., Ross, S., Spiegelman, B., and Ricquier, D. (1994) Characterization
of the novel brown adipocyte cell line HIB 1B. Adrenergic pathways involved in regulation of uncoupling protein gene expression.
J. Cell Sci.
107, 313–319.
|
| |
| 11. |
Forest, C., Doglio, A., Ricquier, D., and Ailhaud, G. (1987) A preadipocyte clonal line from mouse brown adipose tissue. Short-and
long-term responses to insulin and β-adrenergics. Exp. Cell Res.
168, 218–232.
|
| |
| 12. |
Néchad, M., Kuusela, P., Carneheim, C., Björntorp, P., Nedergaard, J., and Cannon, B. (1983) Development of brown fat cells
in monolayer culture. I. Morphological and biochemical distinction from white fat cells in culture. Exp. Cell Res.
149, 105–118.
|
| |
| 13. |
Hikichi, Y., Sugihara, H., and Sugimoto, E. (1993) Differentiation of brown adipose cells in three-dimensional collagen cell
culture. Path. Res. Pract.
189, 73–82.
|
| |
| 14. |
Forest, C., Doglio, A., Casteilla, L., Ricquier, D., and Ailhaud, G. (1987) Expression of the mitochondrial uncoupling protein
in brown adipocytes. Absence in brown preadipocytes and BFC-1 cells. Modulation by isoproterenol in adipocytes. Exp. Cell Res.
168, 233–246.
|
| |
| 15. |
Kuusela, P., Rehnmark, S., Jacobsson, A., Cannon, B., and Nedergaard, J. (1997) Adrenergic stimulation of lipoprotein lipase
gene expression in rat brown adipocytes differentiated in culture: mediation via β3-and α1-adrenergic receptors. Biochem. J.
231, 759–767.
|
| |
| 16. |
Masuno, H., Schultz, C. J., Park, J.-W., Blanchette-Mackie, E. J., Mateo, C., and Scow, R. O. (1991) Glycosylation, activity
and secretion of lipoprotein lipase in cultured brown adipocytes of newborn mice. Effect of tunicamycin, monensin, 1-deoxymannojirimycin
and swainsonine. Biochem. J.
277, 801–809.
|
| |
| 17. |
Rehnmark, S., Néchad, M., Herron, D., Cannon, B., and Nedergaard, J. (1990) α-and β-Adrenergic induction of the expression
of the uncoupling protein thermogenin in brown adipocytes differentiated in culture. J. Biol. Chem.
265, 16,464–16,471.
|
| |
| 18. |
Kopecky, J., Baudysová, M., Zanotti, F., JanÃková, D., Pavelka, S., and Houstek, J. (1990) Synthesis of mitochondrial uncoupling
protein in brown adipocytes differentiated in cell culture. J. Biol. Chem.
265, 22,204–22,209.
|
| |
| 19. |
Bronnikov, G., Houstek, J., and Nedergaard, J. (1992) β-Adrenergic, cAMP-mediated stimulation of proliferation of brown fat
cells in primary culture. Mediation via β1 but not via β3 receptors. J. Biol. Chem. 267, 2006–2013.
|
| |
| 20. |
Thonberg, H., Zhang, S.-J., Tvrdik, P., Jacobsson, A., and Nedergaard, J. (1994) Norepinephrine utilizes α1-and β-adrenoreceptors synergistically to maximally induce c-fos expression in brown adipocytes. J. Biol. Chem. 269, 33,179–33,186.
|
| |
| 21. |
Alvarez, R., de Andrés, J., Yubero, P., Vinas, O., Mampel, T., Iglesias, R., Giralt, M., and Villarroya, F. (1995) A novel
regulatory pathway of brown fat thermogenesis: Retinoic acid is a transcriptional activator of the mitochondrial uncoupling
protein gene. J. Biol. Chem.
270, 5666–5673.
|
| |
| 22. |
Bronnikov, G., Bengtsson, T., Kramarova, L., Golozoubova, V., Cannon, B., and Nedergaard, J. (1999) β1 to β3 switch in control of cAMP during brown adipocyte development explains distinct β-adrenoceptor subtype mediation of proliferation
and differentiation. Endocrinology
140, 4185–4197.
|
| |
| 23. |
Sugihara, H., Miyabara, S., Yonemits, N., and Ohta, K. (1983) Hormonal sensitivity of brown fat cells of fetal rats in monolayer
culture. Exp. Clin. Endocrinol.
82, 309–319.
|
| |
| 24. |
Lorenzo, M., Roncero, C., Fabregat, I., and Benito, M. (1988) Hormonal regulation of rat foetal lipogenesis in brown-adipocyte
primary cultures. Biochem. J.
251, 617–620.
|
| |
| 25. |
Teruel, T., Valverde, A. M., Navarro, P., Benito, M., and Lorenzo, M. (1998) Inhibition of PI 3-kinase and RAS blocks IGF-I
and insulin-induced uncoupling protein 1 gene expression in brown adipocytes. J. Cell. Physiol.
176, 99–109.
|
| |
| 26. |
Shimizu, Y. and Shimazu, T. (1994) Effects of wortmannin on increased glucose transport by insulin and norepinephrine in primary
culture of brown adipocytes. Biochem. Biophys. Res. Commun.
202, 660–665.
|
| |
| 27. |
Nikami, H., Shimizu, Y., Sumida, M., Minokoshi, Y., Yoshida, T., Saito, M., and Shimazu, T. (1996) Expression of β3-adrenoceptor and stimulation of glucose β3-agonists in brown adipocyte primary culture. J. Biochem.
119, 120–125.
|
| |
| 28. |
Champigny, O., Holloway, B. R., and Ricquier, D. (1992) Regulation of UCP gene expression in brown adipocytes differentiated
in primary culture. Effects of a new β-adrenoceptor agonist. Mol. Cell. Endocrinol.
86, 73–82.
|
| |
| 29. |
Chaudhry, A. and Granneman, J. G. (1999) Differential regulation of functional responses by β-adrenergic receptor subtypes
in brown adipocytes. Am. J. Physiol.
277, R147–R153.
|
| |
| 30. |
Klaus, S., Cassard-Doulcier, A.-M., and Ricquier, D. (1991) Development of Phodopus sungorus brown preadipocytes in primary cell culture: Effect of an atypical beta-adrenergic agonist, insulin, and triiodothyronin
on differentiation, mitochondrial development, and expression of the uncoupling protein UCP. J. Cell Biol.
115, 1783–1790.
|
| |
| 31. |
Klaus, S., Ely, M., Encke, D., and Heldmaier, G. (1995) Functional assessment of white and brown adipocyte development and
energy metabolism in cell culture. Dissociation of terminal differentiation and thermogenesis in brown adipocytes. J. Cell Sci.
108, 3171–3180.
|
| |
| 32. |
Casteilla, L., Nouguès, J., Reyne, Y., and Ricquier, D. (1991) Differentiation of ovine brown adipocyte precursor cells in
a chemically defined serum-free medium. Importance of glucocorticoids and age of animals. VEur. J. Biochem.
198, 195–199.
|
| |
| 33. |
Cigolini, M., Cinti, S., Brunetti, L., Bosello, O., Osculati, F., and Björntorp, P. (1985) Human brown adipose cells in culture.
Exp. Cell Res.
159, 261–266.
|
| |
| 34. |
Kuusela, P., Herva, R., Hirvonen, J., Nedergaard, J., and Cannon, B. (1985) Differentiation in vitro of preadipocytes originated
from human brown fat. Acta Physiol. Scand.
124(Suppl. 542), 399–399.
|
| |
| 35. |
Abumrad, N. A., Forest, C. C., Regen, D. M., and Sanders, S. (1991) Increase in membrane uptake of long-chain fatty acids
early during preadipocyte differentiation. Proc. Natl. Acad. Sci. USA
88, 6008–6012.
|
| |
| 36. |
Sasaki, A., Sivaram, P., and Goldberg, I. J. (1993) Lipoprotein lipase binding to adipocytes: evidence for the presence of
a heparin-sensitive binding protein. Am. J. Physiol.
265, E880–E888.
|
| |
| 37. |
Kozak, U. C., Held, W., Kreutter, D., and Kozak, L. P. (1992) Adrenergic regulation of the mitochondrial uncoupling protein
gene in brown fat tumor cells. Mol. Endocrinol.
6, 763–772.
|
| |
| 38. |
Kozak, U. C. and Kozak, L. P. (1994) Norepinephrine-dependent selection of brown adipocyte cell lines. Endocrinology
134, 906–913.
|
| |
| 39. |
Rohlfs, E. M., Daniel, K. W., Premont, R. T., Kozak, L. P., and Collins, S. (1995) Regulation of the uncoupling protein gene
(Ucp) by β1, β2, and β3-adrenergic receptor subtypes in immortalized brown adipose cell lines. J. Biol. Chem.
270, 10,723–10,732.
|
| |
| 40. |
Ross, S. R., Choy, L., Graves, R. A., Fox, N., Solevjeva, V., Klaus, S., Ricquier, D., and Spiegelman, B. M. (1992) Hibernoma
formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene. Proc. Natl. Acad. Sci. USA
89, 7561–7565.
|
| |
| 41. |
Klaus, S., Champigny, O., Cassard-Doulcier, A.-M., Choy, L., Spiegelman, B., and Ricquier, D. (1994) Cell lines derived from
brown fat tumour of transgenic mice: new tools for the study of brown adipocyte development, in Obesity in Europe 1993, (Ditschuneit, H., Gries, F. A., Hauner, H., Schusdziarra, V., and Wechsler, J. G., eds.), John Libbey, London, pp. 65–72.
|
| |
| 42. |
Benito, M., Porras, A., and Santos, E. (1993) Establishment of permanent brown adipocyte cell lines achieved by transfection
with SV40 large T antigen and ras genes. Exp. Cell Res.
209, 248–254.
|
| |
| 43. |
Navarro, P., Valverde, A. M., Benito, M., and Lorenzo, M. (1999) Activated Ha-ras induces apoptosis by association with phosphorylated
Bcl-2 in a mitogen-activated protein kinase-independent manner. J. Biol. Chem.
274, 18,857–18,863.
|
| |
| 44. |
Zennaro, M.-C., Le Menuet, D., Viengchareun, S., Walker, F., Ricquier, D., and Lombès, M. (1998) Hibernoma development in
transgenic mice identifies brown adipose tissue as a novel target of aldosterone action. J. Clin. Invest.
101, 1254–1260.
|
| |
| 45. |
Irie, Y., Asano, A., Canas, X., Nikami, H., Aizawa, S., and Saito, M. (1999) Immortal brown adipocytes from p53-knockout mice:
differentiation and expression of uncoupling proteins. Biochem. Biophys. Res. Commun.
255, 221–225.
|
| |