SpringerProtocols: Abstract: Identification and Isolation of Rodent Lung Dendritic Cells

Identification and Isolation of Rodent Lung Dendritic Cells

By: Philip A. Stumbles⁴, Jennifer Thomas⁴, Patrick G. Holt⁴

Abstract

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Dendritic cells (DC) are a trace cell population found in most tissues that display potent antigen acquisition and presentation capabilities and are unique among antigen-presenting-cell types in their ability to activate unprimed T cells (1). DC are particularly prominent at the mucosal surfaces of the lung and gastrointestinal tract, where they are thought to play a critical role in the regulation of immune responses to environmental antigens (2-4).

Affiliation(s): (4) Division of Cell Biology, TVW Telethon Institute for Child Health Research, West Perth, Australia

Book Title: Dendritic Cell Protocols

Series: Methods in Molecular Medicine | Volume: 64 | Pub. Date: Aug-01-2001 | Page Range: 73-83 | DOI: 10.1385/1-59259-150-7:73

Subject: Microbiology

References

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