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Extraction of RNA from Intracellular Mycobacterium tuberculosis: Methods, Considerations, and Applications
Abstract
Pathogenicity in Mycobacterium tuberculosis may be thought of as a multifactorial process with both pathogen and host-response effector molecules contributing to the process of infection, leading either to immunopathology and disease or control of infection and long-term persistence. Little is known about this at a genetic level, but it is becoming recognized that bacterial virulence constitutes the correct temporal and spatial regulation of many genes that may be necessary for a particular phase in infection in response to specific environmental cues.
Series: Methods in Molecular Medicine  |  Volume: 54  |  Pub. Date: May-19-2001  |  Page Range: 31-42  |  DOI: 10.1385/1-59259-147-7:031
Subject:  Microbiology
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