SpringerProtocols: Abstract: Therapeutic Inhibition of Angiogenesis

Therapeutic Inhibition of Angiogenesis

By: Hua-Tang Zhang², Roy Bicknell²

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The idea of antiangiogenesis as a therapeutic strategy has been around for several decades (1). Vigorously pursued as a novel anticancer strategy (reviewed in (2–6), it is now widely considered to be a promising approach to the treatment of a range of pathologies of which uncontrolled vascular proliferation is a component (see Table 1). To date, therapeutic benefit has been achieved with antiangiogenic therapy in the treatment of life-threatening infantile hemangioma, pulmonary hemangiomatosis, and in the treatment of some vascular tumors (7,8).

Affiliation(s): (2) Molecular Angiogenesis Laboratory,Imperial Cancer Research Fund;Institute of Molecular Medicine, University of Oxford; John Radcliffe Hospital, Oxford, UK

Book Title: Angiogenesis Protocols

Series: Methods in Molecular Medicine | Volume: 46 | Pub. Date: Mar-16-2001 | Page Range: 3-26 | DOI: 10.1385/1-59259-143-4:003

Subject: Cell Biology

References

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