SpringerProtocols: Abstract: The Purification of Mouse Hematopoietic Stem Cells at Sequential Stages of Maturation

The Purification of Mouse Hematopoietic Stem Cells at Sequential Stages of Maturation

By: Sean J. Morrison³

Abstract

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Hematopoietic stem cells (HSCs) are rare, self-renewing progenitors that give rise to all lineages of blood cells. HSCs can be found in all hematopoietic organs, from the para-aortic mesoderm (1),(2) and yolk sac (3),(4) in fetuses to the bone marrow (reviewed in ref. 5), blood and spleens of adults.

Affiliation(s): (3) Departments of Internal Medicine and Cell and Developmental Biology, Howard Hughes Medical Institute and University of Michigan, Ann Arbor, MI

Book Title: Hematopoietic Stem Cell Protocols

Series: Methods in Molecular Medicine | Volume: 63 | Pub. Date: Dec-16-2001 | Page Range: 15-28 | DOI: 10.1385/1-59259-140-X:015

Subject: Cell Biology

References

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