SpringerProtocols: Abstract: From Linkage to Genes: Positional Cloning

From Linkage to Genes: Positional Cloning

By: Stephen Bevan², Richard S. Houlston³

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Linkage analysis in families containing affected individuals can be used to identify the location of disease susceptibility genes. The aim of this chapter is to provide an overview of the molecular methods employed to clone these susceptibility genes on the basis of linkage data.

Affiliation(s): (2) Institute of Cancer Research, Sutton, Surrey, UK
(3) Haddow Laboratory, Institute of Cancer Research, Sutton, Surrey, UK

Book Title: Celiac Disease: Methods and Protocols

Series: Methods in Molecular Medicine | Volume: 41 | Pub. Date: Apr-01-2000 | Page Range: 21-31 | DOI: 10.1385/1-59259-082-9:021

Subject: Microbiology

References

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