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Causes and Consequences of Damage to Mitochondria: Morphological Aspects
Abstract
In recent years the role played by mitochondria in cellular aging has become the focus of intensive research. The concept that these energy-producing organelles are involved in aging derives from the views of Harman (1) and Gerschman (2) linking senescence to the damaging effects of free radicals, especially those released in the mitochondrial respiratory chain.
Affiliation(s): (2) Institute of Neurosciences, Faculty of Medicine, Miguel Hernandez University, San Juan, Alicante, Spain
(3) Neurobiology of Aging Laboratory, INCRA, Ancona, Italy
Series: Methods in Molecular Medicine  |  Volume: 38  |  Pub. Date: May-26-2000  |  Page Range: 221-235  |  DOI: 10.1385/1-59259-070-5:221
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