SpringerProtocols: Abstract: 10. Site-Directed Antibodies as Tools for Investigating Structure and Function of Cytoskeleton Proteins

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10. Site-Directed Antibodies as Tools for Investigating Structure and Function of Cytoskeleton Proteins

By: Walter Steffen², Julie L. Hodgkinson³

Abstract

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The cytoskeleton is a complex structure composed of three distinct filament systems, micro filaments (actin), intermediate filaments, and microtubules. Each filament system consists of filamentous polymers and their associated proteins. Some of the associated proteins are capable of interconnecting the different filaments systems. The function of the cytoskeleton is manifold; not only is the cytoskeleton responsible for maintaining cell integrity and cell shape; it is also involved in cell locomotion and intracellular transport.

Affiliation(s): (2) FB Biologie, Institut für Zellphysiologie und Biosystemtechnik, Universität Rostock, Rostock, Germany
(3) National Heart and Lung Institute, Cardiac Medicine,Imperial College of Science, Technology, and Medicine, London, UK

Book Title: Cytoskeleton Methods and Protocols

Series: Methods in Molecular Biology | Volume: 161 | Pub. Date: Nov-15-2000 | Page Range: 121-132 | DOI: 10.1385/1-59259-051-9:121

Subject: Cell Biology

References

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