SpringerProtocols: Abstract: 4. Video-Enhanced Microscopy for Analysis of Cytoskeleton Structure and Function

4. Video-Enhanced Microscopy for Analysis of Cytoskeleton Structure and Function

By: George M. Langford²

Abstract

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The cytoskeleton is a dynamic network of filaments in the cytoplasm of cells and functions as the roadways for vesicular transport. Of the three types of cytoskeletal filaments, both microtubules and actin filaments have been shown to support vesicle transport. The transport of vesicles is mediated by molecular motors and members of all three super-families of molecular motors-myosin, kinesin and cytoplasmic dynein-have been shown to function as vesicle motors (1–4). The specific types of vesicles transported by some of the molecular motors have been identified (4–6).

Affiliation(s): (2) Department of Biological Sciences, Dartmouth College, Hanover, NH

Book Title: Cytoskeleton Methods and Protocols

Series: Methods in Molecular Biology | Volume: 161 | Pub. Date: Nov-15-2000 | Page Range: 31-43 | DOI: 10.1385/1-59259-051-9:031

Subject: Cell Biology

References

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