SpringerProtocols: Abstract: Rapid Chronocoulometric Measurements of Norepinephrine Overflow and Clearance in CNS Tissues

Rapid Chronocoulometric Measurements of Norepinephrine Overflow and Clearance in CNS Tissues

By: Greg A. Gerhardt⁴

Abstract

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The widespread innervation of norepinephrine (NE) in the mammalian central nervous system (CNS) has continually challenged the neuroscience community to explain the multifaceted roles of this important neurotransmitter. Work over the last three decades has shown that the NE appears to be involved in many CNS functions relating to arousal, fine motor control, stress, pain, learning, and memory. In addition, controversy still exists as to the direct or indirect involvement of NE in psychiatric illnesses, such as depression, schizophrenia, and mania.

Affiliation(s): (4) Departments of Psychiatry and Pharmacology, Neuroscience Training Program and the Rocky Mountain Center for Sensor Technology at the University of Colorado Health Sciences Center, Denver, CO

Book Title: Voltammetric Methods in Brain Systems

Series: Neuromethods | Volume: 27 | Pub. Date: Apr-27-1995 | Page Range: 117-151 | DOI: 10.1385/0-89603-312-0:117

Subject: Neuroscience

References

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