Lipopolysaccharide Chemotyping
Lipopolysaccharide (LPS), traditionally termed somatic antigen or O-antigen, forms an integral part of the outer membrane
of Gram-negative bacteria. In general, LPS consists of essentially three parts:
| 1. |
A hydrophobic portion, lipid A, which is composed of long-chain fatty acids and which anchors LPS molecules into the outer
membrane;
|
| 2. |
The core region; and
|
| 3. |
The long-chain LPS, which is comprised of polymers of oligosaccharide units and contains the epitopes involved in LPS serotyping
reactions.
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Affiliation(s): (3) Division of Enteric Pathogens, Central Public Health Laboratory, London, UK Series: Methods in Molecular Biology | Volume: 46 | Pub. Date: May-23-1995 | Page Range: 41-48 | DOI: 10.1385/0-89603-297-3:41
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