SpringerProtocols: Abstract: Staden: Statistical and Structural Analysis of Protein Sequences

Contents of this article

Browse by Subject

Upload a Protocol

Upload your own protocols for personal use.

Protocol Alert

Receive e-mail notifications about new content on SpringerProtocols.

Video Protocols

View our video protocols.

Call for video protocols.

Comments

Read comments by other users and add your own.

Favorites

Save your favorite protocols to your My Protocols area.

RSS

RSS Feeds

Inside SpringerProtocols

Useful Tools

Staden: Statistical and Structural Analysis of Protein Sequences

By: Rodger Staden²

Abstract

Full Text

Download PDF (230K)

This chapter describes the use of routines for plotting hydrophobicity, charge, and hydrophobic moments, drawing helix wheels and predicting secondary structure. Use of all these routines is very straightforward, and they are contained in the program PIP.

Affiliation(s): (2) MRC Laboratory of Molecular Biology, Cambridge, UK

Book Title: Computer Analysis of Sequence Data: Part II

Series: Methods in Molecular Biology | Volume: 25 | Pub. Date: Feb-08-1994 | Page Range: 125-130 | DOI: 10.1385/0-89603-276-0:125

Subject: Genetics/Genomics

Comments (Loading...)

Post comment/View all comments

1.	Kyte, J. and Doolittle, R. F. (1982) A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105–132.

2.	Eisenberg, D., Schwarz, E. Komaromy, M., and Wall, R. (1984) Analysis of membrane and surface protein sequences with the hydrophobic moment plot. J. Mol. Biol. 179, 125–142.

3.	Schiffer, M. and Edmundson, A. B. (1967) Use of helical wheels to represent the structures of proteins and to identify the segments with helical potential. Biophys. J. 7, 121–135.

4.	Gamier, J., Osguthorpe, D J, and Robson, B. (1978) Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins J Mol Biol. 120, 97–120.