| Albic-Kolbah T., Kajfez F, Rendic S, Sunjic V, Konowal A., and Snatzke G. (1979) Circular dichroism and gel filtration study
of binding of prochiral and choral 1,4-benzodiazepin-2-ones to human serum albumin Biochem Pharmacol.
28, 2457–2464.
|
| |
Alho H., Costa E., Ferrero P, Fujimoto M., Cosenza-Murphy D., and Guidotti A. (1985) Diazepam binding inhibitor: A neuropeptide
located in selected neuronal populations of rat brain Science, 229 179–182.
|
| |
Asano T. and Ogasawara N. (1980) Solubilisation of γ-aminobutyric acid receptor from rat brain. Life Sci
26, 1131–1137.
|
| |
Asano T. and Ogasawara N. (1981) Soluble gamma-aminobutyric acid and benzodiazepine receptors from rat cerebral cortex. Life Sci.
29, 193–200.
|
| |
Baraldi M., Guidotti A, Schwartz J. P., and Costa E. (1979) GABA receptors in clonal cell lines: A model for study of benzodiazepine
action at molecular level. Science
205, 821–823
|
| |
Battersby M. K, Richards J. G, and Mohler H (1979) Benzodiazepine receptor. photoaffinity labeling and localization. Eur. J. Pharmacol
57, 277–278.
|
| |
Beer B., Klepner C. A, Lippa A. S., and Squires R. F. (1978) Enhancement of 3H-diazepam binding by SQ 65396: A novel antianxiety agent. Pharmacol. Biochem. Behav.
9, 849–851.
|
| |
| Biggio G., Corda M. G., de Montis G., and Gessa G. L. (1980) Differential Effects of Kainic Acid on Benzodiazepine Receptors,
GABA Receptors, and GABA-Modulin in the Cerebellar Cortex, in Receptors fog Neurotransmitters and Peptide Hormones. (Pepeu G., Kuhar M. J., and Enna S. J., eds.), pp. 265–270, Raven, New York.
|
| |
| Biscoe T. J, Fry J. P, Martin I. L., and Rickets C. (1981) Binding of GABA and benzodiazepine receptor ligands in the spinal
cord of the spastic mouse. J. Physiol. (Lond.) 317, 32-33P.
|
| |
Biscoe T. J., Fry J. P., and Rickets C. (1984) Autoradiography of benzodiazepine receptor binding in the central nervous system
of the normal C57BL6J mouse J. Physiol. (Lond ) 352, 495–508.
|
| |
Blair T. and Webb G A. (1977) Electronic factors in the structure-activity relationship of some 1,4-benzodiazepine-2-ones.
J Med. Chem.
20, 1206–1210
|
| |
Blanchard J. C, Boireau A, Garret C., and Joulou L. (1979) In vitro and in vivo inhibition by zopiclone of benzodiazepine
binding to rodent brain receptors. Life Sci.
24, 2417–2420.
|
| |
Blount J. F, Fryer R I., Gilman N W., and Todaro L J. (1983) Quinazolines and 1,4-benzodiazepines: 92. Conformational recognition
of the receptor by 1,4-benzodiazepines. Mol Pharmacol.
24, 425–428.
|
| |
Braestrup C., Albrechtsen R., and Squires R F. (1977) High densities of benzodiazepine receptors in human cortical areas Nature (Lond) 269, 702–704.
|
| |
Braestrup C., Honore T., Nielsen M., Petersen E. N., and Jensen L. J (1984) Ligands for benzodiazepine receptors with positive
and negative efficacy. Biochem. Pharmacol.
33, 859–862.
|
| |
Braestrup C. and Nielsen M. (1978) Ontogenetic development of benzodiazepine receptors in the rat brain. Brain Res.
147, 170–173.
|
| |
Braestrup C. and Nielsen M. (1980) Multiple benzodiazepine receptors. Trends Neurosci.
3, 301–303.
|
| |
Braestrup C and Nielsen M. (1981a) 3H-propyl β-carboline-3-carboxylate as a selective radioligand for the Bz1 benzodiazepine receptor subclass. J Neurochem.
37, 333–341.
|
| |
Braestrup C. and Nielsen M (1981b) GABA reduces binding of 3H-methyl β-carboline-3-carboxylate to brain benzodiazepine receptors. Nature (Lond.) 294, 472–474.
|
| |
Braestrup C., Nielsen M., Biggie G., and Squires R. F. (1979) Neuronal localisation of benzodiazepine receptors in cerebellum.
Neurosci Lett.
13, 219–224.
|
| |
Braestrup C., Nielsen M., and Honore T. (1983) Binding of [3H]-DMCM, a convulsive benzodiazepine ligand, to rat brain membranes: Preliminary studies. J. Neurochem.
41, 454–465.
|
| |
| Braestrup C, Nielsen M., Skovbjerg H., and Gredal O. (1981) β-Carboline-3-Carboxylates and Benzodiazepine Receptors, in GABA and Benzodiazepine Receptors. (Costa E., Di Chiara G., and Gessa G L, eds.), pp, 147–155, Raven, New York.
|
| |
Braestrup C., Nissen C., Squires R. F., and Schousboe A. (1978) Lack of brain specific benzodiazepine receptors on mouse primary
astroglial cultures. Neurosci. Lett
9, 45–49
|
| |
Braestrup C., Schmiechen R., Neff G., Nielsen M., and Pettersen E. N (1982) Interaction of convulsive ligands with benzodiazepine
receptors. Science
216, 1241–1243.
|
| |
Braestrup C., and Squires R. F. (1977) Specific benzodiazepine receptors in rat brain characterised by high affinity [3H]-diazepam binding Proc. Natl. Acad. Sci USA
74, 3805–3809.
|
| |
Braestrup C and Squires R F (1978) Brain specific benzodiazepine receptor. Brit. J Psychiatry.
133, 249–260
|
| |
| Brown C. L. and Martin I. L. (1982) Photoaffinity labeling of the benzodiazepine receptor does not occlude the βCCE binding
site Brit. J. Pharmacol.
77, 312P.
|
| |
Brown C L. and Martin I L (1984a) Autoradiographic localization of benzodiazepine receptors in the rat pituitary gland. Eur. J Pharmacol.
102, 563–564
|
| |
Brown C. L. and Martin I. L (1984b) Photoaffinity labeling of the benzodiazepine receptor compromises the recognition site
but not its effector mechanism J. Neurochem.
43, 272–273.
|
| |
Brown C. L. and Martin I. L. (1984c) Kinetics of [3H]-Ro 15-1788 binding to membrane-bound rat brain benzodiazepine receptors. J. Neurochem
42, 918–923
|
| |
| Butcher H. J., Chananont P, Hamor T. A, and Martin I L (1984) Structure activity relationships in a series of 5-phenyl-1,4-benzodiazepines.
Proc. 8th Int Symp Med Chem, Uppsala, Sweden.
|
| |
Candy J. M and Martin I. L (1979a) Is the benzodiazepine receptor coupled to a chloride anion channel? Nature (Lond.) 280, 172–173
|
| |
Candy J M. and Martin I L (1979b) The postnatal development of the benzodiazepine receptor in the cerebral cortex and cerebellum
of the rat. J Neurochem
32, 655–658
|
| |
Chan C Y., Gibbs T T, Borden L. A., and Farb D. H (1983) Multiple embryonic benzodiazepine binding sites: evidence for functionality
Life Sci
33, 2061–2069.
|
| |
Chang L. R and Barnard E A (1982) The benzodiazepine/GABA receptor complex. molecular size in brain synaptic membranes and
in solution. J Neurochem
39, 1507–1518.
|
| |
Chang R. S. L. and Snyder S H (1978) Benzodiazepine receptors labeling in intact animals with [3H]-flunitrazepam. Eur J Pharmacol
48, 213–218.
|
| |
Chang R. S L., Tran V. T, and Snyder S. H. (1980) Neurotransmitter receptor localisations. brain lesion-induced alterations
in benzodiazepine, GABA, β-adrenergic and histamine Hl-receptor binding. Brain Res.
190, 95–110
|
| |
Chiu T. H., Dryden D. M., and Rosenberg H. C, (1982) Kinetics of 3H-flunitrazepam binding to membrane-bound benzodiazepine receptors. Mol. Pharmacol.
21, 57–65
|
| |
Chiu T. H. and Rosenberg H. C (1983) Multiple conformational states of benzodiazepine receptors. Trends Pharmacol Sci
4, 348–350.
|
| |
Costa T., Rodbard D, and Pert C. (1979) Is the benzodiazepine receptor coupled to a chloride anion channel? Nature (Lond) 277, 315–317
|
| |
Costa T, Russell L, Pert C B, and Rodbard D (1981) Halide and γ-aminobutyric acid-induced enhancement of diazepam receptors
in rat brain. Reversal by olisulfonic acid stilbene blockers of anion channels. Mol. Pharmacol.
20, 470–476.
|
| |
| Cowan P. J., Green A R, Nutt D J., and Martin I L. (1981) Ethyl β-carboline carboxylate lowers seizure threshold and antagonises
flurazepam induced sedation in rats. Nature (Lond.) 290, 54–55
|
| |
Crippen G. M. (1982) Distance geometry analysis of the benzodiazepine binding site. Mol Pharmacol.
22, 11–19.
|
| |
Czernik A J, Petrack B., Kalinsky H J., Psychoyos S, Cash W D, Tsai C., Rinehart R K., Granat F. R., Lovell R A., Brundish
D E, and Wade R (1982) CGS 8216, receptor binding characteristics of a potent benzodiazepine antagonist Life Sci
30, 363–372.
|
| |
Davis L G. and Cohen R. K (1980) Identification of an endogenous peptide ligand for the benzodiazepine receptor. Biochem Biophys Res. Commun
92, 141–148.
|
| |
Davis L. G., McIntosh H, and Reker D. (1981) An endogenous ligand to the benzodiazepine receptor: preliminary evaluation of
its bioactivity. Pharmacol Biochem. Behav.
14, 839–844.
|
| |
Doble A. (1983) Comparative thermodynamics of benzodiazepine receptor ligand interactions in rat neuronal membranes. J. Neurochem.
40, 1605–1612.
|
| |
| Doble A., Martin I L, and Richards D A (1982) GABA modulation predicts biological activity of ligands for the benzodiazepine
receptor. Brit. J. Pharmacol
76, 238P.
|
| |
| Dorow R, Horowski R, Paschelke, G Amin, M, and Braestrup C. (1983) Severe anxiety induced by FG7142, a β-carboline ligand
for benzodiazepine receptors. Lancet
ii, 98–99
|
| |
Duka T., Hollt V., and Herz A. (1979) In viva receptor occupation by benzodiazepines and correlation with pharmacological
effect Brain Res.
179, 147–156.
|
| |
| Fernholm B, Nielsen M., and Braestrup C. (1979) Absence of brain specific benzodiazepine receptors in cyclostomes and elasmobranchs.
Camp. Biochem. Physiol
C62, 209–211
|
| |
Franklin T. J. (1980) Binding energy and the activation of hormone receptors Biochem Pharmacol
29, 853–856.
|
| |
Fritz L. C., Wang C. C., and Gorio A. (1979) Avermectin Bla irreversibly blocks postsynaptic potential at the lobster neuromuscular
junction by reducing muscle membrane resistance. Proc Natl Acad Sci USA
76, 2062–2066.
|
| |
| Fryer R. I (1983) Benzodiazepine ligand-receptor interactions, in The Benzodiazepines. From Molecular Biology to Clinical
Practice, (Costa E., ed), pp 7–20, Raven, New York.
|
| |
| Fryer R. I., Gilman N. W., Madison V., and Walser A. (1984) Conformational differences for agonists and antagonists at the
benzodiazepine receptor. Proc 8th Int. Symp Med. Chem. Uppsala, Sweden.
|
| |
Fujimoto M., Hirai K, and Okabayashi T. (1982) Comparison of the effects of GABA and chloride ion on the affinities of ligands
for the benzodiazepine receptor. Life Sci
30, 51–57.
|
| |
| Fuxe K, Koehler C, Agnati L F, Andersson K, Oegren S O., Eneroth P., Perez de la Mora M., Karobath M., and Krogsgaard-Larsen
P (1981) GABA and benzodiazepine receptors Studies on their Localisation in the Hippocampus and Their Interaction With Central
Dopamine Neurons in the Rat Brain, in. GABA and Benzodiazepine Receptors (Costa E, Di Chiara G., and Gessa G. L., eds.), pp. 61–76, Raven, New York
|
| |
Gallager D. W., Mallorga P, Oertel W., Henneberry R, and Tallman J (1981) 3H-diazepam binding in mammalian central nervous system. a pharmacological characterization. J. Neurosci
1, 218–225
|
| |
Gavish M., Chang R S L, and Snyder S. H (1979) Solubilisation of histamine H-l, GABA and benzodiazepine receptors. Life Sci.
25, 783–790.
|
| |
Gavish M. and Snyder S. H (1980) Soluble benzodiazepine receptors GABAergic regulation. Life Sci
26, 579–582
|
| |
Gee K. W. and Yamamura H. I. (1982) Differentiation of benzodiazepine receptor agonist and antagonist sparing of 3H-benzodiazepine antagonist binding following the photolabeling of benzodiazepine receptors. Eur. J Pharmacol.
82, 239–241
|
| |
| Gilli G., Borea P. A, Bertolasi V., and Sacerdoti M. (1977) Stereochemical and electronic properties of benzodiazepines Correlation
with their anti-convulsant activity Proc 4th Eur. Crystallography Meet Oxford, p. 38.
|
| |
| Gilli G. (1984) Crystal structure and properties of molecules Acta Cryst A40 suppl. C-6
|
| |
| Guidotti A., Ebstein B., and Costa E. (1981) Purification and characterisation of an endogenous brain peptide that competes
with 3H-diazepam binding Soc Neurosci. Abs.
7, 634.
|
| |
Guidotti A., Forchetti C. M, Corda M G., Konkel D, Bennett C. D, and Costa E. (1983) Isolation, characterisation, and purification
to homogeneity of an endogenous polypeptide with agonistic action on benzodiazepine receptors. Proc. Natl. Acad. Sci. USA
80, 3531–3535.
|
| |
Guidotti A., Toffano G., and Costa E. (1978) An endogenous protein modulates the affinity of GABA and benzodiazepine receptors
in rat brain. Nature (Lond.) 275, 553–555.
|
| |
Haefely W. (1978) Central actions of benzodiazepines. general introduction. Brit. J Psychiatry
133, 231–238.
|
| |
| Haefely W. (1984) Actions and Interactions of Benzodiazepine Agonists and Antagonists at GABAergic Synapses, in Actions and lnteractions of GABA and Benzodiazepines, (Bowery N. G., ed.), pp. 263–285, Raven, New York.
|
| |
Hirsch J. D. (1982) Photolabeling of benzodiazepine receptors spares [3H]propyl β-carboline binding. Pharmacol Biochem. Behav.
16, 245–248.
|
| |
Honore T., Nielsen M., and Braestrup C. (1983) Binding of 3H-DMCM to benzodiazepine receptors; chloride-dependent allosteric mechanisms. J. Neural. Transm.
58, 83–98.
|
| |
| Honore T., Nielsen M., and Braestrup C. (1984) Barbiturate shift as a tool for determination of efficacy of benzodiazepine
receptor ligands. Eur. J. Pharmacol.
16, 245–248
|
| |
Huang A., Barker J. L., Paul S. M., Moncada V., and Skolnick P. (1980) Characterisation of benzodiazepine receptors in primary
cultures of fetal mouse brain and spinal cord neurons. Brain Res.
190, 485–491.
|
| |
Hunkeler W., Mohler H., Pieri L, Polc P., Bonetti E. P., Cumin R., Schaffner R., and Haefely W. (1981) Selective antagonists
of benzodiazepines. Nature (Lond.) 290, 514–516.
|
| |
Jensen L. H., Peteresen E. N, and Braestrup C. (1983) Audiogenic selzures in DBA/2 mice discriminate sensitively between low
efficacy benzodiazepine receptor agonists and inverse agonists Life Sci
33, 393–399.
|
| |
Johnson R. W. and Yamamura H. I. (1979) Photoaffinity labeling of the benzodiazepine receptor in bovine cerebral cortex Life Sci
25, 1613–1620.
|
| |
Karobath M. and Supavilai P. (1982) Distinction of benzodiazepine agonists from antagonists by photoaffinity labeling of benzodiazepine
receptors in vitro Neurosci Lett.
31, 65–69.
|
| |
Kataoka Y., Gutman Y., Guidotti A., Panula P. Wroblewski J., Cosenza-Murphy D., Wu J Y., and Costa E. (1984) Intrinsic GABAergic
system of adrenal chromaffin cells. Proc. Natl. Acad. Sci. USA
81, 3218–3222.
|
| |
Kochman R. L. and Hirsch J. D. (1982) Thermodynamic changes associated with benzodiazepine and alkyl β-carboline-3-carboxylate
binding to rat brain homogenates Mol. Pharmacol.
22, 335–341
|
| |
| Kuhar M. J. (1978) Histochemical Localisation of Neurotransmitter Receptors, in: Neurotransmitter Receptor Binding (Yamamura H I, Enna S. J, and Kuhar M J., eds), pp 113–126, Raven, New York
|
| |
Lakoski J M., Aghajanian G. K., and Gallager D W. (1983) Interaction of histamine H2-receptor antagonists with GABA and benzodiazepine binding sites in the CNS Eur. J Pharmacol.
88, 241–245.
|
| |
Leeb-Lundberg F, Snowman A, and Olsen R W (1980) Barbiturate receptors are coupled to benzodiazepine receptors. Proc Nat1 Acad Sci USA
77, 7468–7472
|
| |
Leeb-Lundberg F., Snowman A., and Olsen R. W (1981) Perturbation of benzodiazepine receptor binding by pyrazolopyridines involves
picrotoxinin/barbiturate receptor sites. J Neurosci
1, 471–477
|
| |
Levy R. A (1977) The role of GABA in primary afferent depolarization Prog. Neurobiol.
9, 211–267
|
| |
Lippa A. S., Critchett D. J., Sano M. C, Klepner C. A., Greenblat F. N, Coupet J., and Beer B (1979) Benzodiazepine receptors
cellular and behavioural characteristics. Pharmacol Biochem. Behav
10, 831–843
|
| |
Lippa A. S., Sano M C., Coupet J, Klepner C A and Beer B. (1978) Evidence that benzodiazepine receptors reside on cerebellar
Purkinje cells Studies with “nervous” mutant mice Life Sci.
23, 2213–2218
|
| |
Lucek R W. and Coutinho C. B (1976) The role of substituents in the hydrophobic binding of the 1,4-benzodiazepines by human
plasma proteins. Mol. Pharmacol
12, 612–619
|
| |
| Lucek R. W., Garland W A., and Dairman W (1979) CNDO/2 molecular orbital study of selected 1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-ones
Fed Proc
38, 541.
|
| |
Mackerer C R. and Kochman R. L. (1978) Effects of cations and anions on the binding of [3H]-diazepam to rat brain. Proc Soc. Exp Biol Med
158, 393–397
|
| |
Mallorga P., Hamburg M., Tallman J F., and Gallager D W (1980) Ontogenetic changes in GABA modulation of brain benzodiazepine
binding Neuropharmacology
19, 405–408.
|
| |
Mann E. and Enna S J (1980) Phylogenetic distribution of bicuculline sensitive γ-aminobutyric acid (GABA) receptor binding
Brain Res
184, 367–373
|
| |
Marangos P. J, Patel J., Boulenger J P., and Clark-Rosenberg R (1982) Characterisation of peripheral-type benzodiazepine binding
sites in brain using [3H]Ro 5-4864 Mol. Pharmacol
22, 26–32.
|
| |
Martin I. L (1980) Endogenous ligands for benzodiazepine receptors Trends Neurosci
3, 299–301
|
| |
Martin I. L, Brown C L., and Doble A. (1983) Multiple benzodiazepine receptors: structures in the brain or structures in the
mind? A critical review. Life Sci
32, 1925–1933
|
| |
Martin I L. and Candy J. M (1978) Facilitation of benzodiazepine binding by sodium chloride and GABA. Neuropharmacology
17, 993–998
|
| |
Martin I. L. and Candy J. M. (1980) Facilitation of specific benzodiazepine binding in rat brain membrane fragments by a number
of anions. Neuropharmacology
19, 175–179.
|
| |
Martini C., Lucacchini A., Ronca G., Hrelia S., and Rossi C. A. (1982) Isolation of putative benzodiazepine receptors from
rat brain membranes by affinity chromatography. J. Neurochem.
38, 15–19.
|
| |
Massotti M and Guidotti A, (1980) Endogenous regulators of benzodiazepine recognition sites. Life Sci.
27, 847–854.
|
| |
| Mathews G. and Wickelgren W. O. (1979) Glycine, GABA and synaptic inhibition of reticulospinal neurones of lamprey. J Physiol (Lond) 293, 393–415
|
| |
McCarthy G D. and Harden T K. (1981) Identification of two benzodiazepine binding sites on cells cultured from rat cerebral
cortex. J Pharmacol. Exp. Ther
216, 183–191
|
| |
Meiners B. A and Salama A. J (1982) Enhancement of benzodiazepine and GABA binding by the novel anxiolytic tracazolate. Eur. J Pharmacol
78, 315–322.
|
| |
Mitchell P R and Martin I L. (1980) Ethyl β-carboline-3-carboxylate antagonises the effect of diazepam on a functional GABA
receptor. Eur. J Pharmacol
68, 513–514.
|
| |
Mitchell P. R. and Wilson L. (1984) Investigation of the effects of muscimol on different components of 3H-propyl β-carboline-3-carboxylate binding to rat hippocampal and cerebellar membranes. Eur j Pharmacol.
97, 315–319.
|
| |
| Mohler H (1981) Benzodiazepine receptors are there endogenous ligands in brain? Trends Pharmacol Sci.
1, 116–119
|
| |
Mohler H (1982) Benzodiazepine receptors: differential interaction of benzodiazepine agonists and antagonists after photoaffinity
labeling with flunitrazepam. Eur J. Pharmacol.
80, 435–436.
|
| |
Mohler H., Battersby M. K., and Richards J G. (1980) Benzodiazepine receptor protein identified and visualized in brain tissue
by a photoaffinity label. Proc Natl. Acad Scl. USA
77, 1666–1670.
|
| |
Mohler H. and Okada T. (1977) Benzodiazepine receptor. demonstration in the central nervous system. Science
198, 849–851.
|
| |
Mohler H. and Okada T (1978) The benzodiazepine receptor in normal and pathological human brain. Brit J Psychiatry
133, 261–268.
|
| |
Mohler H. and Richards J G (1981) Agonist and antagonist benzodiazepine receptor interaction in vitro. Nature (Lond.) 294, 763–765.
|
| |
| Muller W E., Schlafer U, and Wollert U. (1978) Benzodiazepine receptor binding in rat spinal cord membrane Neurosci. Lett
9, 239–243.
|
| |
Nielsen M. and Braestrup C. (1980) Ethyl β-carboline-3-carboxylate shows differential benzodiazepine receptor interaction
Nature (Lond.) 286, 606–607.
|
| |
Nielsen M, Braestrup C., and Squires R. F. (1978) Evidence for a late evolutionary appearance of brain-specific benzodiazepine
receptors. an investigation of 18 vertebrate and 5 invertebrate species. Brain Res
141, 342–346.
|
| |
Nielsen M., Schou H, and Braestrup C (1981) [3H]-Propyl β-carboline-3-carboxylate binds specifically to brain benzodiazepine receptors. J. Neurochem
36, 276–285.
|
| |
Nutt D J., Cowen P J., and Little H. J (1982) Unusual interactions of benzodiazepine receptor antagonists. Nature (Lond.) 295, 436–438.
|
| |
Oakley N. R. and Jones B. J. (1982) Differential pharmacological effects of β-carboline-3-carboxylic acid esters Neuropharmacology
21, 587–589
|
| |
Oakley N. R., Jones B. J, and Straughan D. W. (1984) The benzodiazepine receptor ligand CL 218872 has both anxiolytic and
sedative properties in rodents. Neuropharmacology
23, 797–802
|
| |
Olsen R W. (1981) GABA-benzodiazepine-barbiturate receptor interactions J. Neurochem
37, 1–13
|
| |
| Palacios J.M and Kuhar M J (1982) Ontogeny of high affinity GABA and benzodiazepine receptors in rat cerebellum. an autoradiographic
study. Devel Brain Res.
2, 531–539.
|
| |
Palacios J. M, Niehoff D L., and Kuhar M J. (1979) Ontogeny of GABA and benzodiazepine receptors. effects of Triton X-100,
bromide and muscimol. Brain Res.
179, 390–395.
|
| |
Palacios J. M., Niehoff D. L., and Kuhar M. J. (1981) Receptor autoradiography with tritium-sensitive film. potential for
computerised densitometry. Neurosci. Lett
25, 101–105.
|
| |
Penney J B, Frey K, and Young A B (1981) Quantitative autoradiography of neurotransmitter receptors using tritium-sensitive
film. Eur. J Pharmacol.
72, 421–422.
|
| |
Petersen E. N. and Buus-Lassen J (1981) A water-lick conflict paradigm using drug-experienced rats. Psychopharmacology
75, 236–239.
|
| |
| Pole P, Bonetti E. P., Schaffner R., and Haefely W (1982) A three-state model of the benzodiazepine receptor explains the
interactions between the benzodiazepine antagonist Ro 15-1788, benzodiazepine tranquilizers, β-carbolines and phenobarbitone
Naunyn Schmiedeberg’s Arch. Pharmacol
321, 260–264.
|
| |
| Prado de Carvalho L., Grecksch G, Chapouthier G., and Rossier J. (1983) Anxiogenic and non-anxiogenic benzodiazepine antagonists.
Nature (Lond) 301, 64–66
|
| |
Quast U and Mahlmann H. (1982) Interaction of 3H-flunitrazepam with the benzodiazepine receptor. evidence for a ligand-induced conformation change. Biochem Pharmacol
31, 2761–2768.
|
| |
Quast U, Mahlmann H., and Vollmer K. O. (1982) Temperature dependence of the benzodiazepine-receptor interaction. Mol Pharmacol
22, 20–25.
|
| |
Regan J. W., Roeske W. R., and Yamamura H. I. (1980) The benzodiazepine receptor. Its development and its modulation by γ-aminobutyric
acid. J. Pharmacol. Exp Ther.
212, 137–143.
|
| |
Rice K. C., Brossi A., Tallman J., Paul S. M., and Skolnick P. (1979) Irazepine, a non-competitive, irreversible inhibitor
of 3H-diazepam binding to benzodiazepine receptors. Nature (Lond.) 278, 854–855
|
| |
Richards J. G, Schlumpf M., Lichtensteiger W., and Mohler H. (1983) Ontogeny of benzodiazepine binding sites in fetal rat
brain: An in vitro autoradiographic study. Monogr. Neural. Sci.
9, 111–118.
|
| |
| Sarrazin M, Bourdeaux-Pontier M., and Briand C. (1976) Etude de quelques relations structure-activate de benzodiazepines.
Ann. Phys. Biol Med.
9, 211–220.
|
| |
Schlumpf M., Richards J. G., Lichtensteiger W., and Mohler H. (1983) An autoradiographic study of the pre-natal development
of benzodiazepine-binding sites in rat brain. J. Neurosci
3, 1478–1487.
|
| |
Schmidt R. F., Vogel E, and Zimmerman M. (1967) Die Wirkung von Diazepam auf die prasynaptische Hemmung und andere Ruckenmarks
reflexe. Naunyn Schmiedeberg’s Arch. Pharmacol.
258, 69–82.
|
| |
Schoch P., and Mohler H. (1983) Purified benzodiazepine receptor retains modulation by GABA. Eur J. Pharmacol.
95, 323–324.
|
| |
Schoch P., Richards J. G., Haring P., Takacs B, Stàhli C, Staehelin T., Haefeley W and Mohler H. (1985) Co-localisation of
GABAA receptors and benzodiazepine receptors in the brain by monoclonal antibodies. Nature (Lond ) 314, 168–171.
|
| |
Schoemaker H., Boles R. G., Horst W. D., and Yamamura H. I. (1983) Specific high affinity binding sues for [3H]-Ro 5-4864 in rat brain and kidney. J Pharmacol Exp. Ther.
225, 61–69.
|
| |
Sherman-Gold R and Dudai Y. (1980) Solubilisation and properties of a benzodiazepine receptor from calf cortex. Brain Res.
198, 485–490.
|
| |
Sieghart W. and Drexler G. 1983 Irreversible binding of [3H]flunitrazepam to different proteins in various brain regions. J Neurochem 41 47–55
|
| |
Sieghart W. and Karobath M. (1980) Molecular heterogeneity of benzodiazepine receptors. Nature (Lond.) 286, 285–287.
|
| |
Sieghart W and Mayer A (1982) Postnatal development of proteins irreversibly labelled with [3H]-flunitrazepam. Neurosci. Lett.
31, 71–74.
|
| |
Sieghart W. and MÓhler H. (1982) 3H-Clonazepam, like 3H-flunitrazepam, is a photoaffinity label for the central type of benzodiazepine receptors. Eur. J. Pharmacol.
81, 171–173.
|
| |
Sigel E. and Barnard E. A. (1984) A γ-aminobutyric acid/benzodiazepine receptor complex from bovine cerebral cortex. Improved
purification with preservation of regulatory sites and their interactions. J Biol. Chem.
259, 7219–7223.
|
| |
Sigel E., Mamalaki C., and Barnard E A. (1982) Isolation of a GABA receptor from bovine brain using a benzodiazepine affinity
column FEBS Lett.
147, 45–48.
|
| |
Sigel E., Stephenson F A, Mamalaki C., and Barnard E A (1983) A γ-aminobutyric acid/benzodiazepine receptor complex in bovine
cerebral cortex. J Biol Chem
258, 6965–6971
|
| |
Sjodin T., Roosdorp N, and Sjoholm I. (1976) Studies on the binding of benzodiazepines to human serum albumin by circular
dichroism measurements Biochem Pharmacol.
25, 2131–2140
|
| |
Skerritt J. H, Willow M., and Johnston G A. R (1982) Diazepam enhancement of low affinity GABA binding to rat brain membranes.
Neurosci Lett
29, 63–66.
|
| |
Skolnick P., Lock K L, Paugh B, Marango F., Windsor R, and Paul S (1980) Pharmacologic and behavioural effects of EMD 28422,
a novel purine which enhances [3H]-diazepam binding to brain benzodiazepine receptors Pharmacol. Biochem. Behav.
12, 685–689.
|
| |
Skolnick P., Paul S, Crawley J., Lewm E, Lippa A, Clody D, Irmscher K., Saiko O, and Minck K (1983) Antagonism of the anxiolytic
action of diazepam and chlordiazepoxide by the novel imidazopyridines EMD 39593 and EMD 41717 Eur J Pharmacol
88, 319–327
|
| |
Skolnick P., Schweri M. M., Willlams E. F, Moncada V. Y, and Paul S. M (1982) An in vitro binding assay which differentiates
benzodiazepine agonists and antagonists Eur J. Pharmacol.
78, 133–136.
|
| |
Skolnick P., Syapin P. J., Paugh B. A, and Paul S. M (1979) Reduction in benzodiazepine receptors associated with Purkinje
cell degeneration in nervous mutant mice. Nature (Lond ) 277, 397–399.
|
| |
Speth R. C, Wastek C J, Johnson P C., and Yamamura H I. (1978) Benzodiazepine binding in human brain demonstration using 3H-flunitrazepam. Life Sci
22, 859–866
|
| |
Speth R C., Wastek G W, and Yamamura H. I (1979) Benzodiazepine receptors: temperature dependence of 3H-flunitrazepam binding. Life Sci
24, 351–358.
|
| |
Speth R. C. and Yamamura H. I. (1979) Benzodiazepine receptors alterations in mutant mouse cerebellum. Eur. J. Pharmacol.
54, 397–399.
|
| |
Squires R. F, Benson D. I., Braestrup C., Coupet J., Klepner C A., Myers V, and Beer B. (1979) Some properties of brain specific
benzodiazepine receptors New evidence for multiple receptors Pharmacol Biochem. Behav
10, 825–830
|
| |
Squires R. F and Braestrup C (1977) Benzodiazepine receptors in rat brain. Nature (Lond.) 266, 732–734
|
| |
Squires R F, Casida J E, Richardson N M., and Saederup E (1983) [35S]-t-Butylbicyclophosphorothionate binds with high affinity to brain specific sites coupled to γ-aminobutyric acid-A and ion recognition
sites. Mol Pharmacol
23, 326–336.
|
| |
Stephenson F. A. and Olsen R. W. (1982) Solubilisation by CHAPS detergent of barbiturate-enhanced benzodiazepine-GABA receptor
complex J. Neurochem
39, 1579–1586.
|
| |
Sternbach L. H. (1978) The benzodiazepine story. Prog. Drug Res
22, 229–266.
|
| |
| Sternbach L H., Randall L. O., Banziger R, and Lehr H (1968) in Structure Activity Relationships in the 1,4-Benzodiazepine
Series, Drugs Affecting the Central Nervous System. vol. 2, (BurgerA., ed.), pp. 237–264. Marcel Dekker,New Y
|
| |
Study R. E. and Barker J L. (1981) Diazepam and (-)-pentobarbital. fluctuation analysis reveals different mechanisms for potentiation
of gamma-aminobutyric acid responses in cultured central neurons. Proc. Natl. Acad Sci. USA
78, 7180–7184.
|
| |
| Sunjit V., Lisini A., Sega A, Kovac T., Kajfez F., and Rustic B (1979) Conformation of 7-chloro-5-phenyl-d5-3(S)-methyl-dihydro-l,-4-benzodiazepin-2-one in solution. J Heterocyclic Chem.
16, 757–761
|
| |
Supavilai P. and Karobath M. (1979) Stimulation of benzodiazepine receptor binding by SQ 20009 is chloride-dependent and picrotoxin-sensitive.
Eur. J Pharmacol.
60, 111–113
|
| |
Supavilai P. and Karobath M. (1980) Heterogeneity of benzodiazepine receptors in rat cerebellum and hippocampus. Eur. J. Pharmacol
64, 91–93.
|
| |
Supavilai P. and Karobath M. (1981) Action of pyrazolpyridines as modulators of 3H-flunitrazepam binding to the GABA/benzodiazepine receptor complex in the cerebellum. Eur. J Pharmacol.
70, 183–193.
|
| |
Supavilai P and Karobath M (1984) [35S]-t-butylbicyclophosphorothionate binding sites are constituents of the γ-aminobutyric acid benzodiazepine receptor complex J. Neurosci.
4, 1193–1200.
|
| |
| Syapm P. J. and Skolnick P (1979) Characterisation of benzodiazepine binding sites in cultured cells of neural origin. J Neurochem.
32, 1047–1051.
|
| |
Takeuchi A and Takeuchi N. (1975) The structure-activity relationship for GABA and related compounds in the crayfish muscle.
Neuropharmacology
14, 627–634
|
| |
Tallman J. F., Thomas J. W, and Gallager D. W. (1978) GABAergic modulation of benzodiazepine binding site sensitivity Nature (Lond.) 274, 383–385
|
| |
Tallman J. F, Thomas J. W., and Gallager D. W (1979) Identification of diazepam binding in intact animals. Life Sci.
24, 873–880.
|
| |
Tenen S S., and Hirsch J D (1980) Antagonism of diazepam activity by β-carboline-3-carboxylic acid ethyl ester. Nature (Lond.) 288, 609–610.
|
| |
Thomas J. W. and Tallman J. F. (1981) Characterisation of photoaffinity labelling of benzodiazepine binding sites. J. Biol. Chem
256, 9838–9842.
|
| |
Ticku N. K. and Olsen R W. (1978) Interaction of barbiturates with dihydropicrotoxinin binding sites related to the GABA receptor-ionophore
system. Life Sci.
22, 1643–1652.
|
| |
Toll L., Keys C., Spangler D, and Loew G (1984) Computer-assisted determination of benzodiazepine receptor heterogeneity.
Eur. J Pharmacol
99, 203–209
|
| |
Unnerstall J. R, Niehoff D. L, Kuhar M. J, and Palacios J M (1982) Quantitative receptor autoradiography using 3H-Ultrofilm. application to multiple benzodiazepine receptors J Neurosci. Methods
6, 59–73.
|
| |
Weiland G. A., Minneman D. P., and Molinoff P. B. (1979) Fundamental differences between the molecular interaction of agonists
and antagonists with the β-adrenergic receptor Nature (Lond) 281, 114–117
|
| |
White W. F., Dichter M. A, and Snodgrass S. R. (1981) Benzodiazepine binding and interactions with the GABA receptor complex
in living cultures of rat cerebral cortex. Brain Res
215, 162–176.
|
| |
Williams E F, Rice K. C., Paul S M, and Skolnick P. (1980) Heterogeneity of benzodiazepine receptors in the central nervous
system demonstrated with kenazepine, an alkylating benzodiazepine J. Neurochem.
35, 591–597
|
| |
Williams M. and Risley E. A. (1979) Enhancement of binding to rat brain membranes in vitro by SQ 20009, a novel anxiolytic
agent, gamma-aminobutyric acid and muscimol. Life Sci
24, 833–841.
|
| |
Williams M and Risley E A (1982) Interactions of avermectins with [3H]β-carboline-3-carboxylate ethyl ester and 3H-diazepam binding sites in rat brain cortical membranes. Eur J Pharmacol
77, 307–312
|
| |
Williams M., and Risley E A. (1984) Ivermectin interactions with benzodiazepine receptors in rat cortex and cerebellum in
vitro. J Neurochem
42, 745–753.
|
| |
Williams M. and Yarbrough G. G. (1979) Enhancement in in vitro binding and some of the pharmacological properties of diazepam
by a novel anthelmintic agent avermectin B1a. Eur. J Pharmacol.
56, 273–276.
|
| |
Williamson M J, Paul S M., and Skolnick P. (1978) Labelling of benzodiazepine receptors in vivo. Nature (Lond ) 275, 551–553.
|
| |
Wong D T., Rathbun R. C, Bymaster F. P., and Lacefield W. B. (1983) Enhanced binding of radioligands to receptors of γ-aminobutyric
acid and benzodiazepines by a new anti-convulsant agent, LY81067 Life Sci
33, 917–923.
|
| |
Woolf J. H. and Nixon J C (1981) Endogenous effector of the benzoidazepine binding site. Purification and characterisation
Biochemistry
20, 4263–4269
|
| |
Yokoyama N., Ritter B., and Neubert A. D. (1982) α-Arylpyrazolo-[4,3-c]quinolin-3-ones. novel agonist, partial agonist and
antagonist of benzodiazepines. J. Med. Chem.
25, 337–339
|
| |
| Young W. S. III and Kuhar M J (1979) Autoradiographic localisation of benzodiazepine receptors in the brains of humans and
animals Nature (Lond.) 280, 393–395.
|
| |
Young W. S. III and Kuhar M. J, (1980) Radiohistochemical localisation of benzodiazepine receptors in rat brain. J. Pharmacol Exp. Ther
212, 337–346.
|
| |
Yousufi M. A. K., Thomas J W, and Tallman J F (1979) Solubilisation of benzodiazepine binding site from rat cortex Life Sci
25, 463–470
|
| |