SpringerProtocols: Abstract: Gene Expression Profiling in the Aging Ovary

5. Gene Expression Profiling in the Aging Ovary

By: Kathleen M. Eyster¹, John D. Brannian²

Abstract

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DNA microarray is an important discovery technology that allows the analysis of the expression of thousands of genes at a time. Data from DNA microarrays elucidate fundamental biological processes through discovery of differential expression of genes not previously known or predicted to be involved in a particular process. In the ovary and other hormone-responsive tissues, the technology can be used to examine the effects of gene mutations, pharmaceutical agents, disease, hormones, developmental changes, or changes in gene expression related to aging.

Affiliation(s): (1) Division of Basic Biomedical Sciences, Sanford School of Medicine, University of South Dakota, Vermillion, SD, USA
(2) Department of Obstetrics and Gynecology, Sanford School of Medicine of The University of South Dakota, Sioux Falls, SD, USA

Book Title: Molecular Endocrinology: Methods and Protocols

Series: Methods in Molecular Biology | Volume: 590 | Pub. Date: Aug-01-2009 | Page Range: 71-89 | DOI: 10.1007/978-1-60327-378-7_5

Subject: Molecular Medicine

Key Words: Microarray - ovary - aging - obesity - gene expression - CodeLink Whole Mouse Genome microarrays - Agilent RNA 6000 Nano LabChip

References

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