Springer Protocols: Abstract: Prediction Methods for B-cell Epitopes

Prediction Methods for B-cell Epitopes

By: Sudipto Saha³, Gajendra P.S. Raghava^{3 4}

Abstract

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In this chapter, two prediction servers of linear B-cell epiotpes have been described; (i) BcePred, based on physico-chemical properties that include hydrophilicity, flexibility/mobility, accessibility, polarity, exposed surface, turns, and antigenicity and ii) ABCpred, based on recurrent neural network. Both of the servers assist in locating linear epitope regions in a protein.

Affiliation(s): (3) Institute of Microbial Technology, Chandigarh, India
(4) UAMS, BRCII, Little Rock, AR

Book Title: Immunoinformatics: Predicting Immunogenicity In Silico

Series: Methods in Molecular Biology | Volume: 409 | Pub. Date: Jun-21-2007 | Page Range: 387-394 | DOI: 10.1007/978-1-60327-118-9_29

Subject: Immunology

Key Words: B-cell epitope - linear epitope - physico-chemical properties - flexibility - hydrophilicity - surface accessibility - turns - recurrent neural network - vaccine

References

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