Springer Protocols: Abstract: IMGT®, the International ImmunoGeneTics Information System® for Immunoinformatics: Methods for Querying IMGT® Databases, Tools, and Web Resources in the Context of Immunoinformatics

IMGT®, the International ImmunoGeneTics Information System® for Immunoinformatics: Methods for Querying IMGT® Databases, Tools, and Web Resources in the Context of Immunoinformatics

By: Marie-Paule Lefranc³

Abstract

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IMGT ^®, the international ImMunoGeneTics information system^® (http://imgt.cines.fr), was created in 1989 by the Laboratoire d’ImmunoGénétique Moléculaire (LIGM) (Université Montpellier II and CNRS) at Montpellier, France, in order to standardize and manage the complexity of immunogenetics data. IMGT ^® is recognized as the international reference in immunogenetics and immunoinformatics. IMGT ^® is a high quality integrated knowledge resource, specialized in (i) the immunoglobulin (IG), T cell receptors (TR), major histocompatibility complex (MHC) of human and other vertebrates; (ii) proteins that belong to the immunoglobulin superfamily (IgSF) and to the MHC superfamily (MhcSF); and (iii) related proteins of the immune systems (RPI) of any species. IMGT ^® provides a common access to standardized data from genome, proteome, genetics, and three-dimensional (3D) structures for the IG, TR, MHC, IgSF, MhcSF, and RPI. IMGT ^® interactive on-line tools are provided for genome, sequence, and 3D structure analysis. IMGT ^® Web resources comprise 8,000 HTML pages of synthesis and knowledge (IMGT Scientific chart, IMGT Repertoire, IMGT Education, etc.) and external links (IMGT Bloc-notes and IMGT other accesses).

Affiliation(s): (3) Laboratoired’ImmunoGénétique Moléculaire, Institut Universitaire de France, Université Montpellier II, UPR CNRS 1142, Institut de Génétique Humaine, Montpellier Cedex, France

Book Title: Immunoinformatics: Predicting Immunogenicity In Silico

Series: Methods in Molecular Biology | Volume: 409 | Pub. Date: Jun-21-2007 | Page Range: 19-42 | DOI: 10.1007/978-1-60327-118-9_2

Subject: Immunology

Key Words: IMGT - ontology - immunoglobulin - T cell receptor - MHC - IgSF - MhcSF

References

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