Springer Protocols: Abstract: Web-based Computational Tools for the Prediction and Analysis of Post-translational Modifications of Proteins

Web-based Computational Tools for the Prediction and Analysis of Post-translational Modifications of Proteins

By: Vladimir A. Ivanisenko³, Dmitry A. Afonnikov³, Nikolay A. Kolchanov³

Abstract

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The increase in the number of Web-based resources on post-translational modification sites (PTMSs) in proteins is accelerating. The paper presents a set of computational protocols describing how to work with the Internet resources when dealing with PTMSs. The protocols are intended for querying in PTMSs related data bases, search of the PTMSs in the protein sequences and structures, calculating the pI and molecular mass of the PTM isoforms. Thus, the modern bioinformatics prediction tools make feasible to express protein modification in broader quantitative terms.

Affiliation(s): (3) Institute of Cytology and Genetics SB RAS, Novosibirsk State University, Novosibirsk, Russia

Book Title: Post-translational Modifi cations of Proteins: Tools for Functional Proteomics

Series: Methods in Molecular Biology | Volume: 446 | Pub. Date: Apr-04-2008 | Page Range: 363-384 | DOI: 10.1007/978-1-60327-084-7_25

Subject: Protein Science

Key Words: Amino acid sequence - protein 3D structure - protein post-translational modification prediction - Web-based resources - database

References

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