Over the past several decades, embryogenesis knowledge and research have progressed rapidly by taking advantage of the technical advances made in other fields. No field of contemporary biomedical science has been more revolutionized by the techniques of molecular biology than developmental embryology. Despite its inherent controversy, the exploration of the human embryo can unlock many of the answers to our deepest biological questions. The present chapter outlines the methods and protocols written by internationally recognized researchers to analyze different aspects of the embryogenesis process presented in this book. This practical guide covering subjects such as the molecular mechanisms of embryonic development, in vitro fertilization, cloning, and laws and ethical considerations of working with embryos, as well as addressing critical features of fetal and placental development and of uterine biology will aid all those who wish to further unravel the mysteries of human embryogenesis.