SpringerProtocols: Abstract: Ligands, Cell-Based Models, and Readouts Required for Toll-Like Receptor Action

2. Ligands, Cell-Based Models, and Readouts Required for Toll-Like Receptor Action

By: Jérôme Dellacasagrande³

Abstract

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This chapter details the tools that are available to study Toll-like receptor (TLR) biology in vitro. This includes ligands, host cells, and readouts. The use of modified TLRs to circumvent some technical problems is also discussed.

Affiliation(s): (3) OPSONA Therapeutics Ltd., Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James’ Hospital, Dublin 8, Ireland

Book Title: Toll-Like Receptors: Methods and Protocols

Series: Methods in Molecular Biology | Volume: 517 | Pub. Date: Jun-01-2009 | Page Range: 1-18 | DOI: 10.1007/978-1-59745-541-1_2

Subject: Immunology

Key Words: Toll-like receptors - Cell-based assays - Reporter gene assays - TLR ligands

References

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