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Combining Uncaging Techniques with Patch-Clamp Recording and Optical Physiology
Abstract
Patch-clamp recording is a powerful approach to monitoring membrane electrical activity with high temporal resolution. However, the spatial resolution of patch-clamp recording in a distributed structure such as a neuron or a brain slice is limited by the fact that each electrode records from just one point, making recording from more than a very small number of points impractical.
Affiliation(s): (2) Department of Molecular Biology, Princeton University, Princeton, NJ
Series: Neuromethods  |  Volume: 38  |  Pub. Date: Aug-02-2007  |  Page Range: 149-168  |  DOI: 10.1007/978-1-59745-492-6_5
Subject:  Neuroscience
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