Springer Protocols: Abstract: 3. Application of Imaging and Other Noninvasive Techniques in Determining Adipose Tissue Mass

3. Application of Imaging and Other Noninvasive Techniques in Determining Adipose Tissue Mass

By: Wei Shen³, Jun Chen⁴

Abstract

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In vivo adipose tissue quantification is an important tool to characterize phenotypes of obesity, especially in the human. The amount and distribution of adipose tissue is associated with many of the adverse consequences of obesity. Recent studies suggest that adipose tissue is not a single homogeneous compartment. Regional adipose tissue depots vary in biological functions and individual adipose tissue compartments have stronger associations with metabolic conditions than does total adipose tissue mass. Currently there is intense and increasing interest in regional adipose tissue compartments. Computed tomography and magnetic resonance imaging often are used to quantify adipose tissue volumes or cross-sectional adipose tissue areas. Other modalities, including dual-energy absorpti-ometry and magnetic resonance spectroscopy, provide whole-body or regional fat measures instead of adipose tissue mass quantification.

Affiliation(s): (3) Obesity Research Center, St. Luke's-Roosevelt Hospital and Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, USA
(4) Image Reading Lab, Obesity Research Center, St. Luke's-Roosevelt Hospital and Institute of Human Nutrition, Columbia University College of Physicians and Surgeons, New York, USA

Book Title: Adipose Tissue Protocols

Series: Methods in Molecular Biology | Volume: 456 | Pub. Date: Jun-01-2008 | Page Range: 39-54 | DOI: 10.1007/978-1-59745-245-8_3

Subject: Molecular Medicine

Key Words: Magnetic resonance imaging - computed tomography - adipose tissue - visceral adipose tissue - subcutaneous adipose tissue - intermuscular adipose tissue - body composition - abdominal obesity

References

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1.	Wang ZM, Pierson RNJ, Heymsfield SB (1992) The five level model: a new approach to organizing body composition research. Am J Clin Nutr 56:19–28

2.	Chowdhury B, Kvist H, Andersson B, Bjorntorp P, Sjostrom L (1993) CT-determined changes in adipose tissue distribution during a small weight reduction in obese males. Int J Obes Relat Metab Disord 17:685–91

3.	Kvist H, Sjostrom L, Tylen U (1986) Adipose tissue volume determinations in women by computed tomography: technical considerations. Int J Obes Relat Metab Disord 10:53–67

4.	Mitsiopoulos N, Baumgartner RN, Heymsfield SB, Lyons W, Gallagher D, Ross R (1998) Cadaver validation of skeletal muscle measurement by magnetic resonance imaging and computerized tomography. J Appl Physiol 85:115–122

5.	Shen W, Punyanitya M, Wang Z, Gallagher D, St-Onge MP, Albu J, Heymsfield SB, Heshka S (2004) Visceral adipose tissue: relations between single-slice areas and total volume. Am J Clin Nutr 80:271–278

6.	Thomas EL, Saeed N, Hajnal JV, Brynes A, Goldstone AP, Frost G, Bell JD (1998) Magnetic resonance imaging of total body fat. J Appl Physiol 85:1778–1785

7.	Ross R, Leger L, Morris D, Guise JD, Guardo R (1992) Quantification of adipose tissue by MRI: relationship with anthropometric variables. J Appl Physiol 72:787–795

8.	Shen W, Wang Z, Tang H, Heshka S, Punyanitya M, Zhu S, Lei J, Heymsfield SB. (2003). Volume estimates derived in vivo by imaging methods: model comparisons with visible woman as the reference. Obes Res 11:217–225

9.	Ross R (1997) Effects of diet- and exercise-induced weight loss on visceral adipose tissue in men and women. Sports Med 24:55–64

10.	Demerath EW, Shen W, Lee M, Choh A, Czerwinski SA, Siervogel RM, Towne B (2007). Estimation of total visceral adipose tissue with a single MR image. Am J Clin Nutr 85:362–368

11.	Abate N, Garg A, Coleman R, Grundy SM, and Peshock RM (1997) Prediction of total subcutaneous abdominal, intraperitoneal, and retroperitoneal adipose tissue masses in men by a single axial magnetic resonance imaging slice. Am J Clin Nutr 65:403–408

12.	Shen W, Punyanitya M, Chen J, Gallagher D, Albu J, Pi-Sunyer X, Lewis CE, Grunfeld C, Heymsfield SB, Heshka SR (2007) Visceral adipose tissue: relationships between single slice areas at different locations and obesity-related health risks. Int J Obes, 31:763–769

13.	Kuk JL, Church TS, Blair SN, Ross R (2006) Does measurement site for visceral and abdominal subcutaneous adipose tissue alter associations with the metabolic syndrome? Diabetes Care 29:679–684

14.	Shen W, Punyanitya M, Wang Z, Gallagher D, St-Onge MP, Albu J, Heymsfield SB, Heshka S (2004) Total body skeletal muscle and adipose tissue volumes: estimation from a single abdominal cross-sectional image. J Appl Physiol 97:2333–2338

15.	Abate N, Burns D, Peshock RM, Garg A, Grundy SM (1994) Estimation of adipose tissue mass by magnetic resonance imaging: validation against dissection in human cadavers. J Lipid Res 35:1490–1496

16.	Yang GZ, Myerson S, Chabat F, Pennell DJ, Firmin DN (2002) Automatic MRI adipose tissue mapping using overlapping mosaics. MAGMA 4:39–44

17.	Shen W, Wang ZM, Punyanita M, Lei J, Sinav A, Kral JG, Imielinska C, Ross R, Heymsfield SB (2003) Adipose tissue quantification by imaging methods: a proposed classification. Obes Res 11:5–16

18.	Kelley DE, Thaete FL, Troost F, Huwe T, Goodpaster BH (2000) Subdivisions of subcutaneous abdominal adipose tissue and insulin resistance. Am J Physiol Endocrinol Metab 278, E941–E948

19.	Misra A, Garg A, Abate N, Peshock RM, Stray-Gundersen J, Grundy SM (1997) Relationship of anterior and posterior subcutaneous abdominal fat to insulin sensitivity in nondiabetic men. Obes Res 5:93–99

20.	Ross R, Aru J, Freeman J, Hudson R, and Janssen I (2002) Abdominal adiposity and insulin resistance in obese men. Am J Physiol Endocrinol Metab 282: E657–E663

21.	Ross R, Rissanen J, Pedwell H, Clifford J, Shragge P (1996). Influence of diet and exercise on skeletal muscle and visceral adipose tissue in men. J Appl Physiol 81:2445–2455

22.	He Q, Engelson ES, Albu JB, Heymsfield SB, Kotler DP (2003) Preferential loss of omental and mesenteric adipose tissue during growth hormone therapy of HIV-associated lipodystro-phy. J Appl Physiol 94:2051–2057

23.	Gallagher D, Kuznia P, Heshka S, Albu J, Heymsfield SB, Goodpaster B, Visser M, Harris TB (2005) Adipose tissue in muscle: a novel depot similar in size to visceral adipose tissue. Am J Clin Nutr 81:903–010

24.	Janssen I, Fortier A, Hudson R, Ross R (2002) Effects of an energy-restrictive diet with or without exercise on abdominal fat, intermuscular fat, and metabolic risk factors in obese women. Diabetes Care 25:431–438

25.	Ross R (1996) Magnetic resonance imaging provides new insights into the characterization of adipose and lean tissue distribution. Can J Physiol Pharmacol 74:778–785

26.	US National Library of Medicine (1995) Visible Human Project. Visible Human CD-ROM, Version 1.1

27.	Snyder WS, Cooke MJ, Manssett ES, Larhansen LT, Howells GP, Tipton IH (1975) Report of the Task Group on Reference Man, Pergamon, Oxford

28.	Elbers JM, Haumann G, Asscheman H, Seidell JC, Gooren LJ (1997) Reproducibility of fat area measurements in young, non-obese subjects by computerized analysis of magnetic resonance images. Int J Obes Relat Metab Disord 21:1121–1129

29.	Seidell JC, Bakker CJ, van der Kooy K (1990). Imaging techniques for measuring adipose-tissue distribution—a comparison between computed tomography and 1.5-T magnetic resonance. Am J Clin Nutr 51:953–957

30.	Thaete FL, Colberg SR, Burke T, Kelley DE (1995) Reproducibility of computed tomography measurement of visceral adipose tissue area. Int J Obes Relat Metab Disord 19:464–467

31.	Ross R, Leger L, Guardo R, De Guise J, Pike BG (1991) Adipose tissue volume measured by magnetic resonance imaging and computerized tomography in rats. J Appl Physiol 70:2164–2172

32.	Changani KK, Nicholson A, White A, Latcham JK, Reid DG, Clapham JC (2003) A longitudinal magnetic resonance imaging (MRI) study of differences in abdominal fat distribution between normal mice, and lean overexpressers of mitochondrial uncoupling protein-3 (UCP-3). Diabetes Obes Metab 5:99–105

33.	Szczepaniak LS, Babcock EE, Schick F, Dobbins RL, Garg A, Burns DK, McGarry JD, Stein DT (1999) Measurement of intracellular triglyceride stores by H spectroscopy: validation in vivo. Am J Physiol 276:E977–E989

34.	Thomas EL, Taylor-Robinson SD, Barnard ML, Frost G, Sargentoni J, Davidson BR, Cunnane SC, Bell JD (1997) Changes in adipose tissue composition in malnourished patients before and after liver transplantation: a carbon-13 magnetic resonance spectroscopy and gas-liquid chro-matography study. Hepatology 25:178–183

35.	Tinsley FC, Taicher GZ, Heiman ML (2004) Evaluation of a quantitative magnetic resonance method for mouse whole body composition analysis. Obes Res. 12:150–160

36.	Pietrobelli A, Formica C, Wang Z, Heymsfield SB (1996) Dual-energy X-ray absorptiometry body composition model: review of physical concepts. Am J Physiol 271: E941–E951

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