SpringerProtocols: Abstract: of Drug Delivery and Alternative Methods to Electroporation

of Drug Delivery and Alternative Methods to Electroporation

By: Sek-Wen Hui³

Abstract

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This chapter provides an overview of the application of electroporation to areas other than gene delivery. These areas include the delivery of drugs and vaccines to tissues and tumors as well as into and through the skin. Achievements and limitations of electroporation in these areas are presented. Alternative physical methods for gene and drug delivery besides electroporation are described. The advantages and drawbacks of electroporation, compared with these methods, are also discussed.

Affiliation(s): (3) Cancer Biology Department, Roswell Park Cancer Institute, and Department of Molecular and Cellular Biophysics and Biochemistry, University at Buffalo, Buffalo, NY, USA

Book Title: Electroporation Protocols: Preclinical and Clinical Gene Medicine

Series: Methods in Molecular Biology | Volume: 423 | Pub. Date: Dec-21-2007 | Page Range: 91-107 | DOI: 10.1007/978-1-59745-194-9_6

Subject: Biotechnology

Key Words: electrochemotherapy - transdermal - anesthetics - peptide hormone - vaccine - lipoplex and polyplex - magnetofection - gene gun - ultrasound - laser

References

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