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Pregraft Tissue Storage Methods for Intracerebral Transplantation
Abstract
The application of neural transplantation techniques for basic research purposes, and as an experimental therapy for Parkinson’s disease (PD) and Huntington’s disease, has led to an increased interest in donor tissue storage methods. In both research and clinical settings, safe and reliable ways to ensure graft tissue availability on the day of transplantation, the ability to accumulate embryonic tissue from several donors over time, the transport of tissue over long distances, extensive microbiological and immunological testing, and even pretreatment of the graft tissue with neurotrophic or neuroprotective factors, would all require expansion of the time interval between the actual dissection of the donor tissue and its implantation in the host brain.
Affiliation(s): (5) Department of Neuroscience, Guilford Pharmaceuticals Inc., Baltimore, MD, USA
Series: Neuromethods  |  Volume: 36  |  Pub. Date: Oct-20-1999  |  Page Range: 27-40  |  DOI: 10.1007/978-1-59259-690-4_2
Subject:  Neuroscience
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