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Purification of Glycoproteins and Their Use as Immunogens
Abstract
Glycosylation is a major posttranslational modification that produces heterogeneity in a protein and results in a group of structurally different species called glycoforms. Protein-associated oligosaccharides are large, structurally diverse molecules, and the biological roles ascribed to them are numerous. Some of these functions include the following: intercellular adhesion, adhesion of microorganisms, including viruses to target cells, and modulation of immunological activity of polypeptide chains.
Affiliation(s): (2) Department of Biochemistry, University of Gdansk, Poland
Series: Methods in Molecular Biology  |  Volume: 80  |  Pub. Date: Apr-02-1998  |  Page Range: 87-93  |  DOI: 10.1007/978-1-59259-257-9_9
Subject:  Immunology
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