Purification of Glycoproteins and Their Use as Immunogens
| Abstract |
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Glycosylation is a major posttranslational modification that produces heterogeneity in a protein and results in a group of
structurally different species called glycoforms. Protein-associated oligosaccharides are large, structurally diverse molecules,
and the biological roles ascribed to them are numerous. Some of these functions include the following: intercellular adhesion,
adhesion of microorganisms, including viruses to target cells, and modulation of immunological activity of polypeptide chains.
Book Title: Immunochemical Protocols
Series: Methods in Molecular Biology | Volume: 80 | Pub. Date: Apr-02-1998 | Page Range: 87-93 | DOI: 10.1007/978-1-59259-257-9_9
Subject: Immunology
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